Running head: Pharmacogenetics and Epigenetics

Pharmacogenetics and Epigenetics 2

Pharmacogenetics and Epigenetics

In summary, Schiele, Gottschalk & Domschke (2020) stipulates that the origin of mental disorders is very complex and controlled by several factors, including an interplay between environmental and genetic factors. The paper evaluates candidate genes derived from different biological processes to prove the effect of environmental factors on the human genome. The environment and genes are interlinked by epigenetic mechanisms like DNA and histone modifications, while microRNAs are the translator. Hence, exposure to environmental factors like stress and anxiety often leads to a specific shape for epigenetic patterns leading to an alteration of the genome in a persons lifespan if they are consistently exposed to environmental factors that affect their mental health. However, epigenetic alterations are reversible through psychotherapy.

Pharmacogenetics is the process used to determine the bodys response to certain medications. Pharmacogenetic testing on patients with...

The changes affect their ability to metabolize any medication to treat or suppress their mental disorder. According to Miller (2021), epigenetic modifications caused by environmental factors and life stress contribute to the final identification of a particular gene that will be used in determining a genes phenotype. The epigenetic modifications cause DNA methylation in the...…alterations in the 2 CYP450 2D6 genes can identify the basis of photoconversion to establish its interlinkage with putative phenotypes that guide phamarcogenenomics.

In conclusion, future research will significantly impact how psychotherapists prescribe drugs to their patients. With the increasing levels of life stress and other environmental factors, peoples epigenetics continue to be affected. More research will come up to find a solution to this complex interrelation. Therefore, medications for mental health disorders will be prescribed if methods of increasing gene 2 CYP450 2D6, enzyme CYP450 2D6 are found, and epigenetic modifications can be easily reversed. Medical experts are still working hard to solve this significant mystery…